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The validation of a biomarker is a complex process, involving such criteria as specificity (to tobacco smoke), sensitivity, dose-response relationships, inter/intra-individual variability, kinetics, confounders, etc

This is the way of the future, and some people just dont want to change. Reynolds, who lost his father and brother to smoking-related illness, said many businesses are unnecessarily wary of the financial impact of smoking bans because organizations backed by tobacco companies spread fear